تخمین حداکثر نبض اکسیژن (O2Ppeak) بدون استفاده از تست ورزش در افراد مسن (مقاله لاتین)

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Geraldo A. Maranhao Neto a, Ricardo B. Oliveira b, Jonathan N. Myers c,
Paulo T.V. Farinatti a,b,*
a Salgado de Oliveira University, Niteroi, RJ, Brazil
b Rio de Janeiro State University, RJ, Brazil
c Stanford University, Palo Alto, USA

Peak oxygen pulse has been considered a surrogate of cardiovascular function and an independent
predictor of all cause mortality. However, O2Ppeak depends on maximal volitional effort which may limit
its utility in older subjects. The aim of this study was to develop a model to estimate O2Ppeak without
exercise in an elderly sample. This cross-sectional study enrolled 67 community-dwelling older adults
(۶۹٫۴  ۷٫۱ years; 41 men) for the non-exercise model development and 30 community-dwelling older
adults (67.7  ۶٫۴ years; n = 30; 17 men) for cross-validation. The non-exercise model was derived through
hierarchical regression model and cross-validated by means of PRESS statistics and comparison against an
independent sample. Classification accuracy of the model for tertiles of estimated and actual O2Ppeak was
tested by gamma (g) nonparametric correlation. The following prediction equation was generated:
۳٫۴۱۶ + ۰٫۱۳۷  weight (kg) + 1.226  Veterans Specific Activity Questionnaire (VSAQ) (metabolic
equivalents, METs) + 1.987  gender (0 = women, 1 = men)  ۲٫۰۴۵  b-Blockers use (0 = no, 1 = yes) –
 ۰٫۰۴۴  resting heart rate (HR) (R2 = 0.83; standard error of estimate (SEE) = 1.68 mL beat۱). Correlation
in cross-validation group was 0.80 (P < 0.001). A high probability was observed for the model to rank the
values in the same tertile in validation and cross-validation groups (g = 0.98; g = 0.92, respectively, P < 0.05).
In conclusion, O2Ppeak can be estimated with reasonable precision without exercise testing, providing an
alternative for elder subjects not capable to perform maximal effort